ISF-1 is a chemically defined serum-free medium for the culture of hybridoma cell lines and the production of monoclonal antibodies (mAb). Due to the known composition of the serum-free media, there is less variability from batch to batch, which leads to a better comparability of the different experiments. The risk of viral or mycoplasmal contamination is also very low.
Monoclonal antibodies produced in a serum-free medium are easier to purify, saving time in downstream processing. ISF-1 supports cell growth and antibody production without the addition of growth factors.
Compared to other serum-free media, ISF-1 is superior in terms of cell growth, viability and productivity.
